Rosthornin A Things To Know Before You Buy
Chemotherapy was potentiated by E7449 and single agent experienced significant antitumor action in BRCA-deficient xenografts. In addition, E7449 inhibited Wnt/β-catenin signaling in colon cancer cell strains, very likely via TNKS inhibition. Consistent with this probability, E7449 stabilized axin and TNKS proteins resulting in β-catenin de-stabil